L-Pyrrolidone Carboxylic Acid (PCA)

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PCA (L-Pyrrolidone Carboxylic Acid) is a naturally occurring component of the Natural Moisturizing Factor (NMF). It accounts for 12% of the NMF and helps maintain optimal hydration within the stratum corneum. Without it, the stratum corneum loses elasticity, water, and defense. 

PCA is not a trend – it’s a biological constant. 

 

CAT NO: PL-AAD-001 – PCA

Storage: 15–25°C, dry, protected from light

 

L-Pyrrolidone Carboxylic Acid (PCA)

FEATURES AND KIENTICS

L-Pyrrolidone Carboxylic Acid  The Biomimetic Hydration Core 

MW: 129.11 Da
High functional efficiency
Maximum biological compatibility
Highly water-soluble
Deep and sustained hydration
Non-greasy hydration

Mechanism of Action

1
Integrates into NMF biochemical network
2
Binds water molecules via hygroscopic functional groups
3
Supports enzymatic processes involved in barrier repair
Mechanism illustrative image

What's inside ?

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White to off-white fine crystalline powder

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Moisture-protected packaging

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≥98% Pure PCA

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Consistent performance across formulations

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Bulk Amounts Available Now

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Made with no allergen-containing ingredients

Advanced Use Concepts

Molecular hydration serums

Post-procedure dermal recovery systems

Barrier repair products

Common Questions

How is PCA different from traditional humectants?

PCA is biomimetic—it doesn’t just attract water, it integrates into the skin’s natural hydration system.

Is PCA suitable for sensitive skin formulations?

Yes, due to its endogenous nature, it shows excellent compatibility.

Can I use PCA in anhydrous systems?

Yes – its crystalline form disperses beautifully in oils and silicones, then activates upon contact with skin’s moisture.

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