RGD Peptide

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RGD peptides are integrin-binding motifs that mimic extracellular matrix ligands (fibronectin, vitronectin). They target αvβ3 and α5β1 integrins, enabling precise cell adhesion, migration, and angiogenesis. Used in wound healing, tissue engineering, and targeted drug delivery.

 

Peptide TypeSignal and carrier peptide

Cat NumberPLS-SIG-007

PRODUCT INFORMATION

 

 I. TECHNICAL SPECIFICATIONS

Structural / Composition Data

Structure / Formula

Arg–Gly–Asp motif

Molecular Weight

~500–1000 Da (variant dependent)

Appearance

White – Off White Powder

Purity

≥ 95% (HPLC)

Solubility

Soluble in aqueous buffers

Form(s) Available

Lyophilized powder / sterile solution

Stability & Shelf Life

Storage

12 months at 2–8 °C, >24 months at –20 °C

Post-Reconstitution

6-12 months at 2–8 °C

Stability Notes

Protect from light

Quality & Compliance

QC Tests

Pending validation

Intended Use

As instructions

Documentation

Available on request

 

 II. PREPARATION / RECONSTITUTION

General Guidance

Reconstitute with 1.0 mL sterile water to obtain 100 mg/mL.

Recommendations

Use within 8–12 hours refrigerated.

 

 III. MECHANISM & BIOLOGICAL FUNCTION

Mechanism of Action

Mimics ECM ligands → binds integrins (αvβ3, α5β1) → promotes adhesion, angiogenesis, and targeted cell delivery.

Biological Claims

  • Integrin-mediated targeting
  • Cell adhesion & migration
  • Angiogenesis induction

 

 IV. APPLICATIONS

Intended Uses

Targeted drug delivery systems

 

 V. PACKAGING & PRESENTATION

Available Sizes / Form

Powder Form

100 mg vials

250 mg vials

500 mg vials

1 g vials

Solution Form

1 mL (10% w/v)

5 mL (10% w/v)

10 mL (10% w/v)

20 mL (10% w/v)

Variants

Linear

Cyclic

 

RGD Peptide

FEATURES AND KIENTICS

A cell-adhesion and targeting peptide containing the Arg–Gly–Asp (RGD) motif, designed to enhance cellular communication and tissue integration. It is widely used in regenerative formulations and targeted delivery systems due to its affinity for integrin receptors. 

Binds selectively to αvβ3 and α5β1 integrins
Promotes cell adhesion and migration
Stimulates angiogenesis and tissue repair
Supports wound closure and dermal regeneration
Multiple Formulations Compatible
Enhances delivery to ischemic or damaged tissues

What's inside ?

Cell adhesion motif; the minimalist tripeptide sequence recognized universally by integrin receptors (αvβ3, αvβ5, α5β1) enabling cell anchoring and migration. 

Linear or cyclic RGD sequence variants

Integrin-binding motif for targeting efficiency

Peptide scaffold with high structural stability

Purity ≥98% verified by HPLC

Ready for biofunctional conjugation

Pharmaceutical-grade powder or aqueous base

Precision Targeting for Regeneration

RGD Peptide is engineered to interact directly with cell surface integrins that control cell adhesion

Guiding therapeutic compounds, nutrients, or bioactives precisely where healing begins.

Non-immunogenic, biocompatible, stable, and highly modular for conjugation to biomaterials.

Common Questions

What makes RGD peptides important in biomedical use?

Their unique integrin-binding capability allows precise targeting of regenerating or ischemic tissues.

Are RGD peptides safe for topical or internal delivery systems?

Yes. They are biocompatible and used in both topical formulations and nanoparticle-based drug delivery.

What’s the difference between linear and cyclic RGD?

Cyclic RGD (cRGDfK) offers higher receptor affinity and stability, making it preferable for advanced delivery technologies.

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