RGD peptides are integrin-binding motifs that mimic extracellular matrix ligands (fibronectin, vitronectin). They target αvβ3 and α5β1 integrins, enabling precise cell adhesion, migration, and angiogenesis. Used in wound healing, tissue engineering, and targeted drug delivery.
Peptide Type: Signal and carrier peptide
Cat Number: PLS-SIG-007
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PRODUCT INFORMATION |
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I. TECHNICAL SPECIFICATIONS |
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Structural / Composition Data |
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Structure / Formula |
Arg–Gly–Asp motif |
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Molecular Weight |
~500–1000 Da (variant dependent) |
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Appearance |
White – Off White Powder |
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Purity |
≥ 95% (HPLC) |
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Solubility |
Soluble in aqueous buffers |
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Form(s) Available |
Lyophilized powder / sterile solution |
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Stability & Shelf Life |
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Storage |
12 months at 2–8 °C, >24 months at –20 °C |
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Post-Reconstitution |
6-12 months at 2–8 °C |
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Stability Notes |
Protect from light |
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Quality & Compliance |
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QC Tests |
Pending validation |
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Intended Use |
As instructions |
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Documentation |
Available on request |
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II. PREPARATION / RECONSTITUTION |
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General Guidance |
Reconstitute with 1.0 mL sterile water to obtain 100 mg/mL. |
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Recommendations |
Use within 8–12 hours refrigerated. |
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III. MECHANISM & BIOLOGICAL FUNCTION |
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Mechanism of Action |
Mimics ECM ligands → binds integrins (αvβ3, α5β1) → promotes adhesion, angiogenesis, and targeted cell delivery. |
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Biological Claims |
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IV. APPLICATIONS |
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Intended Uses |
Targeted drug delivery systems |
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V. PACKAGING & PRESENTATION |
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Available Sizes / Form |
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Powder Form |
100 mg vials |
250 mg vials |
500 mg vials |
1 g vials |
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Solution Form |
1 mL (10% w/v) |
5 mL (10% w/v) |
10 mL (10% w/v) |
20 mL (10% w/v) |
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Variants |
Linear |
Cyclic |
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Cell adhesion motif; the minimalist tripeptide sequence recognized universally by integrin receptors (αvβ3, αvβ5, α5β1) enabling cell anchoring and migration.
Linear or cyclic RGD sequence variants
Integrin-binding motif for targeting efficiency
Peptide scaffold with high structural stability
Purity ≥98% verified by HPLC
Ready for biofunctional conjugation
Pharmaceutical-grade powder or aqueous base
RGD Peptide is engineered to interact directly with cell surface integrins that control cell adhesion
Guiding therapeutic compounds, nutrients, or bioactives precisely where healing begins.
Non-immunogenic, biocompatible, stable, and highly modular for conjugation to biomaterials.
Their unique integrin-binding capability allows precise targeting of regenerating or ischemic tissues.
Yes. They are biocompatible and used in both topical formulations and nanoparticle-based drug delivery.
Cyclic RGD (cRGDfK) offers higher receptor affinity and stability, making it preferable for advanced delivery technologies.