β-WHITE (Oligopeptide-68) is a biomimetic signaling peptide that modulates the MITF (Microphthalmia-Associated Transcription Factor) pathway to downregulate key melanogenesis genes, including TYR, TYRP1, and DCT. By suppressing tyrosinase activity and interfering with melanin synthesis, it effectively reduces hyperpigmentation and brightens the overall skin tone. Beyond depigmentation, it provides antioxidant support and cellular protection against UV-induced oxidative stress. β-WHITE is widely incorporated into brightening serums, pigmentation-correction creams, and even-tone skincare formulations that require clinically verified whitening efficacy with high dermal tolerance.
Peptide Type: Signal and regulatory peptide for pigmentation control
Cat Number: PLS-PIG-002
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PRODUCT INFORMATION |
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I. TECHNICAL SPECIFICATIONS |
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Structural / Composition Data |
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Structure / Formula |
Oligopeptide-68 |
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Molecular Weight |
β-WHITE™ |
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Appearance |
TKMVHMRIKHPDHDH |
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Purity |
~1.8 kDa |
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Solubility |
White to off-white lyophilized powder |
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Form(s) Available |
≥ 99% (HPLC) |
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Stability & Shelf Life |
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Storage |
Store at -20°C, protected from light and moisture |
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Post-Reconstitution |
Stable for 5–7 days at 2–8°C |
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Stability Notes |
Shelf life up to 24 months (lyophilized form) |
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Quality & Compliance |
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QC Tests |
HPLC purity, MS verification, cell-based tyrosinase inhibition assay |
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Intended Use |
Cosmetic ingredient for skin brightening and tone correction |
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Documentation |
CoA, SDS, Technical Data Sheet |
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II. PREPARATION / RECONSTITUTION |
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General Guidance |
Reconstitute in sterile distilled water or buffered saline. Mix gently until clear. |
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Recommendations |
Add directly to the aqueous phase of formulations below 40°C. Avoid strong acids or bases. |
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III. MECHANISM & BIOLOGICAL FUNCTION |
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Mechanism of Action |
Oligopeptide-68 acts as a competitive inhibitor of the MITF (Microphthalmia-Associated Transcription Factor), downregulating melanogenesis-related genes such as TYR, TYRP1, and DCT. This results in reduced melanin synthesis and a more uniform skin tone. |
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Biological Claims |
Decreases skin pigmentation, improves clarity and brightness, reduces dark spots, and promotes even complexion through melanogenesis control. |
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IV. APPLICATIONS |
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Intended Uses |
Brightening serums, pigmentation control creams, whitening lotions, spot-correcting ampoules. |
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V. PACKAGING & PRESENTATION |
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Sizes |
50 mg |
100 mg |
500 mg |
1 g |
A dermatologically engineered peptide solution designed to correct pigmentation and enhance skin radiance.
Oligopeptide-68 bioactive sequence
Stable lyophilized format for advanced formulation
High-purity peptide (≥99% by HPLC)
Synergistic with niacinamide and vitamin C
Designed for controlled release in topical systems
Dermatologically tested for safety and efficacy
β-WHITE redefines skin clarity through molecular precision
Regulating pigment production at the genetic level for a radiant, even complexion.
Melanogenesis-regulating signal peptide designed to balance skin tone by suppressing MITF expression
It works on the transcriptional level, downregulating melanogenesis genes rather than chemically bleaching the skin.
Yes. It pairs effectively with vitamin C, retinoids, and antioxidant serums for synergistic results.
Noticeable improvements in tone and clarity are typically seen after 2–4 weeks of continuous use.
Next-Generation Life Science Products for Everyday Health.